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Candida albicans Kinesin Kar3 Depends on a Cik1-Like
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Candida albicans is a major fungal pathogen whose virulence is associated with its ability to transition from a budding yeast form to invasive hyphal filaments. The kinesin-14 family member CaKar3 is required for transition between these morphological states, as well as for mitotic progression and karyogamy.While kinesin-14 proteins are ubiquitous, CaKar3 homologs in hemiascomycete fungi are ...read more
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The Snf1-activating kinase Sak1 is a key regulator of metabolic adaptation and in vivofitness of Candida albicans Bernardo Ramırez-Zavala, 1Austin Mottola, Julia Haubenreißer, 1Sabrina Schneider, Stefanie Allert,2 Sascha Brunke,2 Knut Ohlsen,1 Bernhard Hube2,3,4 and Joachim Morschh€auser 1* 1Institute for Molecular Infection Biology, University of W€urzburg, W €urzburg, Germany. ...read more
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